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Somatic evolution in cancer
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21	• life began on earth about 3500 million years ago • new species evolved from very simple living things • evidence for evolution is provided by - fossils - comparing DNA • first species developed from molecules w Add to Reading List Source URL: www.knockhardy.org.uk Language: English - Date: 2010-08-06 03:50:02 Evolution Puberty Organism Extinction Natural selection Mutation Species Brain Somatic evolution in cancer Biology Evolutionary biology Philosophy of biology
22	High order chromatin architecture shapes the landscape of chromosomal alterations in cancer Add to Reading List Source URL: mirnylab.mit.edu Language: English - Date: 2012-09-02 12:48:11 Evolutionary biology Cytogenetics Genomics Chromosomes Fractal globule Ridge Chromosome conformation capture Somatic evolution in cancer Karyotype Biology Genetics Philosophy of biology
23	Impact of deleterious passenger mutations on cancer progression Christopher D. McFarlanda, Kirill S. Korolevb, Gregory V. Kryukovc,d, Shamil R. Sunyaeva,c,d, and Leonid A. Mirnya,b,c,e,1 a Graduate Program in Biophysics, Add to Reading List Source URL: mirnylab.mit.edu Language: English - Date: 2013-02-08 15:07:16 Evolutionary biology Mutation Carcinogenesis Somatic evolution in cancer Gene duplication Cancer research Point mutation Cancer stem cell Senescence Biology Medicine Oncology
24	Smallbone et al. Biology Direct 2010, 5:22 http://www.biology-direct.com/contentOpen Access RESEARCH Add to Reading List Source URL: www.biologydirect.com Language: English Carcinogens Histopathology Somatic evolution in cancer Cancer Prostate cancer Epigenetics Acidosis Carcinoma Breast cancer Medicine Oncology Carcinogenesis
25	Biol Philos DOIs10539Cancer cells and adaptive explanations Pierre-Luc Germain ( ) Add to Reading List Source URL: plger.net Language: English - Date: 2012-08-30 07:07:50 Evolutionary biology Developmental biology Stem cells Biotechnology Somatic evolution in cancer Cancer stem cell Cellular differentiation Natural selection Evolution Biology Medicine Carcinogenesis
26	Pharmacogenetic testing affects choice of therapy among women considering tamoxifen treatment Add to Reading List Source URL: genomemedicine.com Language: English Molecular biology Carcinogenesis DNA sequencing Evolutionary biology Biotechnology The Cancer Genome Atlas Full genome sequencing Somatic evolution in cancer Exome sequencing Biology Medicine Oncology
27	Systematic prediction of drug responses for a large panel of cancer cell lines based on attractor landscape analysis of p53 network Minsoo Choi, Jae Il Joo, and Kwang-Hyun Cho‡ Laboratory for Systems Biology and Bio-In Add to Reading List Source URL: ws9.websitepanelonline.com Language: English - Date: 2014-09-08 00:30:36 Apoptosis P53 Programmed cell death Somatic evolution in cancer Biology Medicine Proteins
28	Study uncovers genetic diversity of pancreatic cancer Add to Reading List Source URL: medicalxpress.com Language: English - Date: 2015-04-14 05:55:33 Pancreatic cancer Prostate cancer Cancer Breast cancer Somatic evolution in cancer Daniel Von Hoff Medicine Oncology Carcinogenesis
29	Diverse system stresses: common mechanisms of chromosome fragmentation Add to Reading List Source URL: www.nature.com Language: English - Date: 2011-06-30 06:02:19 Cellular processes Programmed cell death Cell cycle Mitosis Carcinogenesis Centrosome Somatic evolution in cancer Mitotic catastrophe DNA repair Biology Cell biology Apoptosis
30	Insights & Perspectives Think again Targeting cancer’s weaknesses (not its strengths): Therapeutic strategies suggested by the atavistic model Add to Reading List Source URL: www.mso.anu.edu.au Language: English - Date: 2014-08-13 10:32:51 Carcinogenesis Oncology Immune system T cells Cancer immunotherapy Immunotherapy Cancer immunology Somatic evolution in cancer Cancer stem cell Medicine Biology Immunology